What is myCancerProject.org?
We believe that immunologic data sets are more useful and impactful when they are easy to understand, explore and disseminate. The purpose of myCancerProject.org is to host some of the new tools that we are working on to to explore large, complex data sets that are not well-represented by static figures.
In the era of big data, this problem is shared by many research studies. The solution is to develop interactive, visually-oriented, open-access platforms that allow the user to explore the data sets and ask the questions that they find relevant. We have several exciting projects underway, and as we create new visualization tools, we will be adding them here.
My name is Michael McNamara and I am a data scientist with a background in biomedical science. During the development of this project, I was working as a research fellow in the laboratory of Dr. William Redmond at the Providence Portland Medical Center’s Earle A Chiles Research Institute in Portland, Oregon. Currently, I am a member of the analytics team at Moda Health, Oregon’s preeminent health insurance company.
I enjoy developing data solutions to scientific and healthcare challenges. I am interested in developing technological solutions that allow us to integrate healthcare, financial, biomedical and user-generated data sets to create adaptive and scalable data networks that we can leverage to personalize treatments and improve patient outcomes.
My name is Ian Hilgart-Martiszus and I am both a researcher in the Redmond Lab as well as a clinical research associate in the Cancer Clinical Trials program at Providence Cancer Center in Portland, Oregon. In the Redmond Lab I worked with Dr. Michael McNamara on a range of internally and externally sponsored research projects to evaluate the efficacy and mechanisms of novel combinatorial cancer immunotherapy regimens.
My experience with data-rich, frontline molecular biology techniques, as well as immunotherapy cancer drugs, lead me to believe that the tools to effectively fight cancer may currently be available. In order to achieve this I am interested in developing systems that harness biological and patient derived information in a user friendly platform, accessible to anyone with an interest in curing cancer.
The goal of my laboratory is to elucidate the mechanisms by which the provision of co-stimulatory signals in conjunction with checkpoint inhibitor blockade boosts tumor immunotherapy. Specifically, we are interested in how these therapies augment the function and differentiation of tumor-specific T cells.
Another major focus of my laboratory is investigating the mechanisms by which vaccination plus combination immunotherapy rescues anergic CD8 T cells to augment anti-tumor immunity. In addition, we are investigating how tumors suppress T cell-mediated immunity and are developing novel approaches to overcome this hurdle to generate more potent anti-tumor immunity.
- Diego Barragan – Research Associate
- Dana Emerson – Graduate Student (OHSU)
- Haley Gallagher – Undergraduate Intern
- Leah Martin – Undergraduate Intern
myCancerProject.org was awarded top honors in the Research Fast Pitch competition at the Oregon Bioscience Associations 2016 Annual Conference.
The Robert W. Franz Cancer Research Center in the Earle A. Chiles Research Institute is a world-class research facility located within Providence Cancer Center in Portland, Ore. Founded in 1993 by Walter Urba, M.D., Ph.D., director of cancer research, and a team of internationally-recognized scientists, our main area of investigation is cancer immunotherapy, a specialized field of study focused on triggering the immune system to fight cancer.
At the Earle A. Chiles Research Institute, we are dedicated to:
- Discovering how the immune system can be harnessed to fight cancer.
- Developing new cancer therapies and clinical trials from breakthroughs in the research laboratory.
- Collaborating with colleagues across the country and throughout the world to foster state-of-the-art research.
- Partnering with community leaders and philanthropists to raise funding and awareness for cancer research.
- Training the next generation of cancer researchers to continue the fight against cancer.
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